Biomolecular interactions and binding dynamics of inhibitor arachidonic acid, with tyrosinase enzyme.
Shojazadeh T, Zolghadr L, JafarKhani S, Gharaghani S, Farasat A, Piri H, Gheibi N.
Shojazadeh T, et al.
J Biomol Struct Dyn. 2023 Mar;41(4):1378-1387. doi: 10.1080/07391102.2021.2020167. Epub 2022 Jan 3.
J Biomol Struct Dyn. 2023.
PMID: 34974821
Based on the kinetic results, arachidonic acid showed mixed-type of inhibition with Ki = 4.7 M. Fluorescence and CD studies showed changes of secondary and tertiary structures of enzyme and a reduction of alpha-helix* amino acids after its incubation with different concent …
Based on the kinetic results, arachidonic acid showed mixed-type of inhibition with Ki = 4.7 M. Fluorescence and CD studies showed ch …